Membrane plasma filter PFM-800 is the main functional element of all package procurements for plasmapheresis procedures.

Membrane plasma filter PFM-500 is designed for separation of the whole blood on plasma and concentrated red cells during plasmapheresis procedures in order to obtain donor plasma and autoplasma in the blood service institutions, as well as in clinics for detoxification, immune- and reocorrection in public health divisions of toxicology, transfusion, cardiology, nephrology, endocrinology, allergy, pulmonology, oncology, dermatology, narcology, neurogy and others; in obstetrics and gynecology, pediatrics, intensive care, surgery, in clinics, hospitals, ambulance service, in military field medicine, in urgent cases and in conditions of disaster medicine.

A number of different methods of plasmapheresis are used currently in clinical practice. Most of them, however, require centrifuges or other stationary apparatus. Nevertheless, some therapeutic and prophylactic institutions do not have such devices - in hard-to-reach territories without electricity facilities, for example. Only after organization of the industrial production of the first domestic membrane plasma filtrers PFM-800 and development of the technique of non-apparatus membrane plasmapheresis UBM-01-"PF SPb" (the developer and the manufacturer JSC "Plasmofilter", St. Petersburg, patent No. 2113240 dated 05.05.95) procedures of membrane plasmapheresis have became accessible for serial medical institutions, including regional hospitals, medical maternity units, etc.

One of the main causes of the severe neonatal illness and infant mortality is a syndrome of endogenous intoxication, occuring in acute pneumonia, hemolytic disease, hyperbilirubinemia, septic and other complications, when even new antibiotics are helpless. Implementation of detoxification procedures by generally accepted methods of efferent therapy (hemosorbtion and plasmapheresis, - gravity, apparatus or packed) to newborns, especially to premature babies, faces several technical and methodical problems.