It acts on the key component in the pathogenesis of chronic inflammation in joints by decreasing the expression of pro-inflammatory factors (e.g., cytokines and other mediators). A major distinguishing feature is that it does not produce side effects, even with long-term administration. ARTHROFOON® is well compatible with conventional therapies. When used as part of combination treatment, ARTHROFOON® allows for reducing the dose of concomitantly administered steroids and NSAIDs, and even discontinuing their use.